Industrial and precious metal miners fell about 1% each, and banks fell 1.5%.
The domestically focussed mid-cap index declined 0.8%, with capital goods stocks among the worst performers.
Payments specialist Equiniti, which is being bought by New York-based company Siris Capital, could face some job cuts once the deal is closed, the private equity firm said late on Monday. Its shares rose 0.5%.
On the macro front, UK’s labour market showed signs of further recovery as employers added a record-high 207,000 staff to their payrolls in September and separate data showed UK’s unemployment rate fell to 4.5% in the three months to August, reinforcing bets for a sooner Bank of England rate hike.